Relevant publications
Novel dual-lumen
microneedle delivers adeno-
associated viral vectors in
the guinea pig inner ear via
the round window
membrane
DR Hammer, F Voruz, A Aksit, E Breil, F Rousset, P Senn, S Ilmjärv, ES Olson, AK Lalwani, JW Kysar
Biomedical Microdevices 27 (2), 27
Physiologic Effects of
Microneedle‐Mediated
Intracochlear Dexamethasone
Injection in the Guinea Pig
SJ Feng, S Leong, A Aksit, D Hébert, ES Olson, JW Kysar, AK Lalwani
The Laryngoscope 134 (1), 388-392
Microneedles Facilitate
Small-Volume Intracochlear
Delivery Without Physiologic
Injury in Guinea Pigs
S Leong, SJ Feng, A Aksit, ES Olson, JW Kysar, AK Lalwani
Otology & Neurotology 44 (5), 513-519
Inner Ear Diagnostics and
Drug Delivery via
Microneedles
S Leong, A Aksit, SJ Feng, JW Kysar, AK Lalwani
Journal of Clinical Medicine 11 (18), 5474
Novel 3D-printed hollow
microneedles facilitate safe,
reliable, and informative
sampling of perilymph from
guinea pigs
B Szeto, A Aksit, C Valentini, M Yu, EG Werth, S Goeta, C Tang, LM Brown, JW Kysar, AK Lalwani
Hearing research 400, 108141
3D-printed microneedles
create precise perforations
in human round window
membrane in situ
H Chiang, M Yu, A Aksit, W Wang, S Stern-Shavit, JW Kysar, AK Lalwani
Otology & neurotology
Microneedle-mediated
delivery of SiRNA via
liposomal-based
transfection for inner ear
gene therapy
SJ Feng, F Voruz, S Leong, DR Hébert, E Breil, A Aksit, M Yu, L Chiriboga, ES Olson, JW Kysar, AK Lalwani
Otology & Neurotology, 10.1097
Anatomic, physiologic, and
proteomic consequences of
repeated microneedle-
mediated perforations of the
round window membrane
S Leong, A Aksit, B Szeto, SJ Feng, X Ji, RK Soni, ES Olson, JW Kysar, AK Lalwani
Hearing Research 432, 108739
Impact of Systemic versus
Intratympanic
Dexamethasone
Administration on the
Perilymph Proteome
B Szeto, C Valentini, A Aksit, EG Werth, S Goeta, LM Brown, ES Olson, JW Kysar, AK Lalwani
Journal of proteome research 20 (8), 4001-4009
Drug delivery device for the
inner ear: ultra-sharp fully
metallic microneedles
A Aksit, S Rastogi, ML Nadal, AM Parker, AK Lalwani, AC West, JW Kysar
Drug delivery and translational research 11, 214-226
Small molecule delivery
across a perforated artificial
membrane by
thermoreversible
hydrogel poloxamer 407
A Aksit, S Rastogi, ML Nadal, AM Parker, AK Lalwani, AC West, JW Kysar
Drug delivery and translational research 11, 214-226
Microneedle-mediated
intracochlear injection
safely achieves higher
perilymphatic DEX
concentration than
intratympanic delivery in
guinea pig
Voruz F, Feng SJ, Breil E, Yu M, Hammer DR, Aksit A, Zandkarimi F, Olson ES, Kysar JW, Lalwani AK
Drug Delivery and Translational Research, 1-12
Pyrolyzed Ultrasharp
Glassy Carbon Microneedles
C Zhou, A Aksit, B Szeto, RL Li, AK Lalwani, JW Kysar
Advanced Engineering Materials 24 (11), 2201222
Simulation assisted design
for microneedle
manufacturing:
Computational modeling of
two-photon templated
electrodeposition
A Aksit, AK Lalwani, JW Kysar, AC West
Journal of manufacturing processes 66, 211-219
Anatomical and Functional
Consequences of
Microneedle Perforation of
Round Window Membrane
M Yu, DN Arteaga, A Aksit, H Chiang, ES Olson, JW Kysar, AK Lalwani
Otology & neurotology
In-vitro perforation of the
round window membrane
via direct 3-D printed
microneedles
A Aksit, DN Arteaga, M Arriaga, X Wang, H Watanabe, KE Kasza, AK Lalwani, JW Kysar
Biomedical microdevices 20, 1-12
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